Lipid nanoemulsions (NEs) are promising eco-friendly nanocarriers for diagnostic and therapeutic applications. However, functionalizing them with biomolecules, such as antibodies, remains difficult due to the liquid nature of their core. In this study, Andrey Klymchenko's team, with Valeria Jose BOIDE-TRUJILLO as the first author and in…
The RISEst and Alsace France-BioImaging Node platforms are organizing a new training session entitled: "Introduction to bio-image processing and analysis with Fiji/ImageJ" October 30–31, 2025 – Faculty of Pharmacy, Illkirch This free training course, conducted in English, is intended for all academic users of RISEst platforms: students, engineers,…
This year, our laboratory is actively participating in the Science Festival through two major events: Lingolsheim Science Village Léa DENECHERE and Charlène D'ANCONA from the Biophonics of Molecular and Cellular Interactions team will lead the interactive workshop “The World of RNA and Aptamers” (in virtual reality) in collaboration with…
The DNA-PAINT (Point Accumulation for Imaging in Nanoscale Topography) technique exploits transient hybridization of DNA strands to achieve nanometric resolution. Although effective, it remains limited in its standard form by background noise generated by unbound strands and slow image acquisition. In a new study, a project initiated and led by Yv…
Dipanjan Mukherjee and members of the BIMC team led by Yves Mély, along with their collaborators from the Instituto de Química Física Blas Cabrera (IQF-CSIC), the Université de SanDiego, the Istituto Biostrutture eBioimmagini and the Università Di Siena have just published a new article in the international journal Nucleic Acids Research. This…
We are pleased to announce the publication of a scientific article co-authored by several members of the BIMC team: Ludovic Richert, Patrice Rassam, and Yves Mély in Ebiomedecine: “Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia” Background Pseudomonas aeruginosa is an opportunistic bacterium capable of…
We are pleased to announce the publication in the scientific journal Nanoscale (Royal Society of Chemistry) of work carried out by Paraskevi Gaki from Andrey Klymchenko's team in collaboration with BrightSens Diagnostics, as part of a Cifre project. The study presents the development of fluorescent polymer nanoparticles functionalized by DNA…
Olha Tkach and members of the Biophotonics of Molecular and Cellular Interactions team led by Yves Mély, , in collaboration with the Instituto de Química Física Blas Cabrera (IQF-CSIC) de Madrid, the Consiglio Nazionale delle Ricerche - Istituto Biostrutture e Bioimmagini, the Department of Chemistry and Biochemistry- University of California and…
Andrey Klymchenko, Pascal Didier from the Photoactive Materials and Bioimaging team, and Deep Sekhar Biswas ( past member) have co-authored a review entitled: “Light-Harvesting Nanomaterials Based on Dyes for Energy Transfer and Amplified Biosensing”
A new study, coordinated by Drs. hibaut Wolf and Benoît Lhermitte (CHRU de Strasbourg), (Strasbourg University Hospital), has just been published in the journal Acta Neuropathologica Communications. This work is the result of close collaboration between Strasbourg University Hospital, l’ICANS | Strasbourg Cancer Institute,our team OnKO • 3T led by…
The aim of the Laboratory of Bioimaging and Pathology is to use multidisciplinary (biology/chemistry/physics) and multi-scale (from molecule to patient) approaches to study, at both fundamental and applied levels, the properties and roles of a limited number of key biomolecules involved in various pathological processes. Our approach is to develop new therapeutic and diagnostic approaches in oncology and microbiology based on information obtained at the fundamental level. A key feature of the unit is the parallel development and characterisation of innovative fluorescence-based tools, methods and techniques to answer these questions. This multidisciplinary approach, which combines the development of innovative fluorescence and imaging tools to address biological questions, is unique in the French scientific landscape.
Lipid nanoemulsions (NEs) are promising eco-friendly nanocarriers for diagnostic and therapeutic applications. However, functionalizing them with…
The RISEst and Alsace France-BioImaging Node platforms are organizing a new training session entitled: "Introduction to bio-image processing and…
This year, our laboratory is actively participating in the Science Festival through two major events: Lingolsheim Science Village Léa…
The DNA-PAINT (Point Accumulation for Imaging in Nanoscale Topography) technique exploits transient hybridization of DNA strands to achieve nanometric…
Dipanjan Mukherjee and members of the BIMC team led by Yves Mély, along with their collaborators from the Instituto de Química Física Blas Cabrera…
September is International Childhood Cancer Awareness Month. Throughout this month, associations, researchers, clinicians, students, and families are…
We are pleased to announce the publication of a scientific article co-authored by several members of the BIMC team: Ludovic Richert, Patrice Rassam,…
We are pleased to announce the publication in the scientific journal Nanoscale (Royal Society of Chemistry) of work carried out by Paraskevi Gaki from…
Olha Tkach and members of the Biophotonics of Molecular and Cellular Interactions team led by Yves Mély, , in collaboration with the Instituto de…
Andrey Klymchenko, Pascal Didier from the Photoactive Materials and Bioimaging team, and Deep Sekhar Biswas ( past member) have co-authored a review…
A new study, coordinated by Drs. hibaut Wolf and Benoît Lhermitte (CHRU de Strasbourg), (Strasbourg University Hospital), has just been published in t…
Daniel Martina 2025" Football Tournament Illkirch Campus
Andrey Klymchenko, CNRS research director and head of the Photoactive Materials and Bioimaging team, is one of the winners announced by the European…
We are proud to announce that two young researchers from our laboratory have won awards at the Journées du Campus Illkirch (JCI), held on May 26 and…
One and a half day of scientific meeting that bring together researchers from all the campus to learn, network and get creative. With: • The…
New mapping revolutionizes glioblastoma management
We are proud to announce the publication of the work of Nathan Aknine, Rémi Pelletier and Andrey Klymchenko from the Photoactive Materials and…
Klymchenko team, in collaboration with BrightSens Diagnostics and teams of Pfeiffer (UPR9002-CNRS ARN) and Fafi- Kremer (HUS), has developed a…
New probes for imaging lipid droplets Nathan Aknine, a PhD student in the Photoactive Materials and Bioimaging team, recently published a paper with…
UpConverting NanoParticles (UCNPs) are capable of emitting visible light very efficiently after excitation by infrared light. UCNPs’ Anti-Stockes…
Human immunodeficiency virus type 1 (HIV-1) causes AIDS and is a member of envelope viruses in which virus particles are surrounded by a lipid…
Photo-convertible fluorescent probes are able to change their emission color upon light irradiation. This phenomenon is advantageously used in…
Kinetics of protein-assisted nucleic acid interconversion monitored by transient time resolved fluorescence in microfluidic droplets Interconversio…
Intermolecular dark resonance energy transfer (DRET): upgrading fluorogenic DNA sensing FRET sensitivity is usually limited by the spectral…
Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues Isomorphic and expanded fluorescent nucleoside analogues are…
Under the title “What makes thienoguanosine an outstanding fluorescent DNA probe?”, the work of the Laboratory of Bioimaging and Pathologies (CNRS /…
With the title in French « Les photons associent leur énergie pour améliorer l’imagerie », collective data from the Institut pluridisciplinaire Hubert…
The group of A. Klymchenko “Nanochemistry and Bioimaging” developed DNA-functionalized fluorescent polymeric nanoparticles for amplified detection of…
