Active targeting of tumor cells relies on the use of ligands capable of specifically binding to receptors that are overexpressed on their surface, such as EGFR (epidermal growth factor receptor). Among these ligands, monoclonal antibodies and aptamers are promising tools for the targeted delivery of therapeutic molecules (chemotherapy agents,…
Sophie Martin, , head of the OnKO • 3T team, has received a national grant of €60,729 from the JetonsCancer Endowment Fund, an initiative led by Rotary France. This funding, which is entirely dedicated to research, will enable the purchase of a HUMIMIC Chip+ system, a state-of-the-art device for developing innovative “tumors-on-a-chip” models. A…
Elisa Bombarda, a member of the Biophotonics of Molecular and Cellular Interactions team led by Yves Mély, has been selected as a recipient of the IdEx – Research Support Fund 2026 call for proposal ! Her project, « Light from the dark: what the dark states of fluorophores can tell », was selected as part of the University of Strasbourg’s France…
Nanoparticles (NPs) play a key role in biological applications, such as bioimaging and biosensing. Their stealth properties—that is, their ability to avoid nonspecific interactions with biological environments—is essential to ensuring their stability and efficacy in vivo. Until now, polyethylene glycol (PEG) has been the gold standard for imparting…
Strasbourg, May 21 and 22, 2026 – Our laboratory made a significant impact at the 2026 Illkirch Campus Days (JCI) with exceptional participation and two awards.
The team led by Prof. Yves MELY, with Pankhi Singh and Dipanjan Mukherjee as first authors, has just published a major study in the field of structural biology. Their work reveals how thienoguanosine (thG), a fluorescent isomorphic analog of guanosine, enables the exploration of the structure and dynamics of hTel22—a human telomeric G-quadruplex…
Neurotransmitters, such as dopamine, are essential biomarkers for diagnosing neurological disorders (Parkinson’s disease, depression, schizophrenia, etc.). However, their detection in biological fluids remains challenging due to their low concentration (on the order of nanomolar) and their structural similarity to other molecules present in…
We are pleased to invite you to JCI 2026 Illkirch Campus days on Thursday, May 21, and Friday, May 22, at the Pôle API. JCI 2026 is a day-and-a-half-long scientific conference bringing together researchers from across the campus to learn, exchange ideas, and get creative! You are a young researcher ? Come and present your work as an…
The Laboratory of Bioimaging and Pathology is immensely proud to announce that Andrey Klymchenko, director of the Photoactive Materials and Bioimaging team, has been awarded the 2026 CNRS Silver Medal. This prestigious award recognizes the originality, quality, and international impact of his work on fluorescent probes for bioimaging, a field at…
The RISEst and Alsace FBI Node microscopy core facilities are organising a workshops on "Introduction to bio-image processing and analysis with Fiji/ImageJ" the 21th & 22th April (in English) This training is freeand open to all RISEst users (Students, ITA, researchers etc.) frompublic research institutions.Main topics covered: Introduction to…
The aim of the Laboratory of Bioimaging and Pathology is to use multidisciplinary (biology/chemistry/physics) and multi-scale (from molecule to patient) approaches to study, at both fundamental and applied levels, the properties and roles of a limited number of key biomolecules involved in various pathological processes. Our approach is to develop new therapeutic and diagnostic approaches in oncology and microbiology based on information obtained at the fundamental level. A key feature of the unit is the parallel development and characterisation of innovative fluorescence-based tools, methods and techniques to answer these questions. This multidisciplinary approach, which combines the development of innovative fluorescence and imaging tools to address biological questions, is unique in the French scientific landscape.
Active targeting of tumor cells relies on the use of ligands capable of specifically binding to receptors that are overexpressed on their surface,…
Sophie Martin, , head of the OnKO • 3T team, has received a national grant of €60,729 from the JetonsCancer Endowment Fund, an initiative led by Rota…
Elisa Bombarda, a member of the Biophotonics of Molecular and Cellular Interactions team led by Yves Mély, has been selected as a recipient of the IdE…
Nanoparticles (NPs) play a key role in biological applications, such as bioimaging and biosensing. Their stealth properties—that is, their ability to…
Strasbourg, May 21 and 22, 2026 – Our laboratory made a significant impact at the 2026 Illkirch Campus Days (JCI) with exceptional participation and…
The team led by Prof. Yves MELY, with Pankhi Singh and Dipanjan Mukherjee as first authors, has just published a major study in the field of…
Neurotransmitters, such as dopamine, are essential biomarkers for diagnosing neurological disorders (Parkinson’s disease, depression, schizophrenia,…
We are pleased to invite you to JCI 2026 Illkirch Campus days on Thursday, May 21, and Friday, May 22, at the Pôle API. JCI 2026 is a…
The Laboratory of Bioimaging and Pathology is immensely proud to announce that Andrey Klymchenko, director of the Photoactive Materials and Bioimaging…
The RISEst and Alsace FBI Node microscopy core facilities are organising a workshops on "Introduction to bio-image processing and analysis with…
The EN-HOPE SMART4CBT Center of Excellence, led by Natacha ENTZ WERLE, a member of the ONKO3T team, is organizing an international symposium focused…
The Faculty of Pharmacy is proud to announce that Léa DENECHERE and Anthony AUGE, two of its doctoral students, have been selected for the Alsace…
A thematic issue co-edited by researchers from LBP and LIT!
It is with great emotion that we announce the retirement of Monique Dontenwill, CNRS Research Director within our unit. After years of dedication,…
Maeva Martin, first author—under the supervision of Laurence Choulier - and co-directed by Julie Helms - along with Marine Tschirhart, Cyril Auger,…
We would like to extend our warmest congratulations to Pankhi Singh, who defended her thesis under the supervision of Prof. Yves Mély in the…
New mapping revolutionizes glioblastoma management
We are proud to announce the publication of the work of Nathan Aknine, Rémi Pelletier and Andrey Klymchenko from the Photoactive Materials and…
Klymchenko team, in collaboration with BrightSens Diagnostics and teams of Pfeiffer (UPR9002-CNRS ARN) and Fafi- Kremer (HUS), has developed a…
New probes for imaging lipid droplets Nathan Aknine, a PhD student in the Photoactive Materials and Bioimaging team, recently published a paper with…
UpConverting NanoParticles (UCNPs) are capable of emitting visible light very efficiently after excitation by infrared light. UCNPs’ Anti-Stockes…
Human immunodeficiency virus type 1 (HIV-1) causes AIDS and is a member of envelope viruses in which virus particles are surrounded by a lipid…
Photo-convertible fluorescent probes are able to change their emission color upon light irradiation. This phenomenon is advantageously used in…
Kinetics of protein-assisted nucleic acid interconversion monitored by transient time resolved fluorescence in microfluidic droplets Interconversio…
Intermolecular dark resonance energy transfer (DRET): upgrading fluorogenic DNA sensing FRET sensitivity is usually limited by the spectral…
Fundamental photophysics of isomorphic and expanded fluorescent nucleoside analogues Isomorphic and expanded fluorescent nucleoside analogues are…
Under the title “What makes thienoguanosine an outstanding fluorescent DNA probe?”, the work of the Laboratory of Bioimaging and Pathologies (CNRS /…
With the title in French « Les photons associent leur énergie pour améliorer l’imagerie », collective data from the Institut pluridisciplinaire Hubert…
The group of A. Klymchenko “Nanochemistry and Bioimaging” developed DNA-functionalized fluorescent polymeric nanoparticles for amplified detection of…
