Internship

Thesis opportunity: Structural characterization of RNA lipid nanoparticles for therapeutic applications

The Laboratoire de Bioimagerie et Pathologies (UMR7021 - CNRS), located within the Faculty of Pharmacy in Illkirch, is offering an innovative thesis opportunity in the field of biotechnologies and advanced imaging. Our team, renowned for its expertise in biophysics and bio-imaging, is dedicated to exploring fundamental mechanisms and improving cutting-edge therapeutic tools.

Faced with the growing development of nucleic acid-based therapies, notably messenger RNAs (mRNAs) and interfering RNAs (iRNAs), this thesis project aims to overcome the challenges associated with their intracellular delivery by studying lipid nanoparticles (LNPs). These vectors play a key role in the stabilization, vectorization and delivery of RNA therapeutics. However, the internal structure of LNPs, which directly influences their biological efficacy, remains poorly understood.

By joining our laboratory, you will participate in interdisciplinary research combining spectroscopic, microscopic and molecular biology approaches to elucidate the structural characteristics of LNPs. This collaborative project is supported by cutting-edge technologies and prestigious scientific partners, providing a stimulating environment for the development of diverse skills in biophysics, biotechnology and imaging.

Start date: March 2025 Application deadline: 15/01/2025
Info and contact: ludovic.richert@unistra.fr




Every year, we welcome several dozen students for their internship within the framework of their BTS, DUT, Licence, Master and engineering school diplomas.

For further information about internships or to send your curriculum vitae, you can contact the UMR 7021 general office or directly the team leaders.