New JoVE collection: Dmytro Dziuba and Julie Karpenko launch a thematic collection of video articles on advanced fluorescent probes
A thematic issue co-edited by researchers from LBP and LIT!
An exceptional career crowned with the CNRS Medal of Honor!
It is with great emotion that we announce the retirement of Monique Dontenwill, CNRS Research Director within our unit. After years of dedication, scientific rigor, and human generosity, Monique leaves behind an indelible mark. Her career has left its mark on the OnKO3T team through her expertise,…
Aptamers: an innovative therapeutic approach to septic coagulopathy.
Maeva Martin, first author—under the supervision of Laurence Choulier - and co-directed by Julie Helms - along with Marine Tschirhart, Cyril Auger, and Florence Toti from the UMR 1260 Regenerative Nanomedicine unit (University of Strasbourg/Inserm), present a new review published in Annals of…
Congratulations to Pankhi Singh!
We would like to extend our warmest congratulations to Pankhi Singh, who defended her thesis under the supervision of Prof. Yves Mély in the Biophotonics of Molecular and Cellular Interactions team. Her work focused on the study of G-quadruplexes, remarkable nucleic acid structures, and their…
Discover Luminosa: a revolution in lifetime microscopy!
The PIQ-QuESt platform in collaboration with PicoQuant and OPTON LASER internationalinvites you to discover Luminosa, an innovative confocal microscope dedicated to simple, fast, and reliable measurements of single molecules. You will be able to • Explore the latest advances in low-light…
Seminar by David Monchaud "Chemical modulation of G-quadruplex (G4) structures in human cells"
We are pleased to invite you to our next seminar entitled: « Chemical modulation of G-quadruplex (G4) structures in human cells» by David Monchaud. After a PhD in supramolecular chemistry in Geneva and completing two postdoctoral fellowships in medicinal chemistry and chemical biology in Paris,…
We Congratulate Rémi Pelletier on His Success in the CNRS Competition and His Recruitment as a Research Engineer
A Scientific Career Dedicated to Innovation in Biomedical Imaging We are proud to announce Rémi Pelletier’s success in the CNRS competition and his recruitment as a research engineer. After actively contributing to the laboratory’s work as a postdoctoral researcher, Rémi now continues his…
Smart nanofibers for better wound healing monitoring
Rémi Pelletier, Anila Hoskere Ashoka and Andrey Klymchenko, de l'équipe Matériaux photoactifs et bioimagerie, from the Photoactive Materials and Bioimaging team, have developed fluorescent polymer nanofibers that act as multiplexed ratiometric sensors for pH and oxygen, two key parameters in the…
Congratulations to Bohdan Kozibroda!
Bohdan successfully defended his thesis, which was jointly supervised by Andrey Klymchenko's team and Nobel Prize winner Professor Jean-Marie Lehn. Bohdan's work in the Photoactive Materials and Bioimaging team proposes an innovative concept for artificial receptors for the fluorescent detection…
New publication: oShark, a modified fluorescent aptamer resistant to nucleases
A collaborative work of Tanushree Gupta and Andrey Klymchenko with Michael Ryckelynck, Janine KEHRLI and Roger Cubí Piqué from UPR9002-IBMC, Strasbourg, resulted in oShark, a chemically modified light-up aptamer designed to resist degradation in complex biological environments, which is now…
Cellular stress and immunity: a key discovery for phototherapy of squamous cell carcinoma
Photodynamic therapy (PDT) is a promising strategy against head and neck squamous cell carcinoma (HNSCC). In this study led by Chloé Thibaudeau et Alain Jung from the ONKO3T team, in collaboration with Professor Gilles GASSER, they investigated how different ruthenium(II)-based photosensitizers…
New publication : How HIV-1 Gag protein selects host membrane lipids.
We are pleased to announce the publication of a study conducted by Nario TOMISHIGE, Yves MELY, and Toshihide KOBAYASHI on how the HIV-1 Gag protein reorganizes lipids in the host plasma membrane. HIV-1 is enveloped in a membrane derived from the host cell, which is notably enriched in specific…
Nanoparticles that blink... and a team that sheds light on the phenomenon!
New publication: Decoding the blinking of fluorescent polymer nanoparticles Interdisciplinary collaboration between chemists and physicists from Andrey Klymchenko's team— Deep Sekhar Biswas, Benjamin Boglio and Pascal Didier — and theorists from the University of Bologna: Giacomo Fanciullo, Silvia…
Following the scientific publication in Nucleic Acid Research (NAR)
Read Marion Riegert's popular science article published in the University of Strasbourg's Savoir(s) magazine, which explains the role of UHRF1 in the transmission of epigenetic memory in cells. Link : Le mécanisme de la protéine UHRF1 mis en lumière | Savoirs - Le quotidien de l’Université de…
New publication dans Royal Society of Chemistry Nanoscale Advances: a plug-and-play strategy for functionalizing lipid nanoemulsions with antibodies.
Lipid nanoemulsions (NEs) are promising eco-friendly nanocarriers for diagnostic and therapeutic applications. However, functionalizing them with biomolecules, such as antibodies, remains difficult due to the liquid nature of their core. In this study, Andrey Klymchenko's team, with Valeria Jose…
Workshop on "Introduction to bio-image processing and analysis with Fiji/ImageJ October 2025 session
The RISEst and Alsace France-BioImaging Node platforms are organizing a new training session entitled: "Introduction to bio-image processing and analysis with Fiji/ImageJ" October 30–31, 2025 – Faculty of Pharmacy, Illkirch This free training course, conducted in English, is intended for all…
Our laboratory at the 2025 Science Festival - Intelligence(s)
This year, our laboratory is actively participating in the Science Festival through two major events: Lingolsheim Science Village Léa DENECHERE and Charlène D'ANCONA from the Biophonics of Molecular and Cellular Interactions team will lead the interactive workshop “The World of RNA and…
New publication: proof of concept for fast nanoscopy using DNA-PAINT
The DNA-PAINT (Point Accumulation for Imaging in Nanoscale Topography) technique exploits transient hybridization of DNA strands to achieve nanometric resolution. Although effective, it remains limited in its standard form by background noise generated by unbound strands and slow image acquisition. …
A new publication by the BIMC team in Nucleic Acids Research reveals the mechanism of the UHRF1 protein!
Dipanjan Mukherjee and members of the BIMC team led by Yves Mély, along with their collaborators from the Instituto de Química Física Blas Cabrera (IQF-CSIC), the Université de SanDiego, the Istituto Biostrutture eBioimmagini and the Università Di Siena have just published a new article in the…
New publication: an innovative strategy against Pseudomonas aeruginosa
We are pleased to announce the publication of a scientific article co-authored by several members of the BIMC team: Ludovic Richert, Patrice Rassam, and Yves Mély in Ebiomedecine: “Directed-complement killing of Pseudomonas aeruginosa protects against lethal pneumonia” Background Pseudomonas…