Rémi Pelletier, Anila Hoskere Ashoka and Andrey Klymchenko, de l'équipe Matériaux photoactifs et bioimagerie, from the Photoactive Materials and Bioimaging team, have developed fluorescent polymer nanofibers that act as multiplexed ratiometric sensors for pH and oxygen, two key parameters in the wound healing process.
These sensors are based on an innovative FRET-type double energy transfer architecture, enabling signal amplification and reliable measurement based on the intensity ratio between a reference dye and analyte-sensitive acceptors.
The wavelengths used, adapted to RGB systems, enable simultaneous detection of pH and oxygen in a wound model, with simple, remote reading compatible with smartphones.
These materials pave the way for new biomedical applications for non-invasive wound healing monitoring.
The authors would like to thank SATT Connectus and ERC CaptuRel for their support..
Congratulations to the authors on this innovation!
Link : Fluorescent Polymeric Nanofibers as Ratiometric Multiplexed Skin Sensors of pH and Oxygen https://doi.org/10.1002/adhm.202502717
